Intrafamilial spread of the same clarithromycin-resistant Helicobacter pylori infection confirmed by molecular analysis.

نویسندگان

  • Ikue Taneike
  • Keibun Suzuki
  • Saori Nakagawa
  • Tatsuo Yamamoto
چکیده

Clarithromycin-resistant Helicobacter pylori (CRHP) is increasing worldwide, especially in children. We report a family case in which both the mother and child were infected with CRHP. DNA analysis revealed that all of the mother's and daughter's isolates were indistinguishable, suggesting that the same CRHP strain spread between the family members. The spread of CRHP within families may be increasing.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Adding ofloxacin to standard triple-drug regimens increased the Helicobacter pylori eradication rate: Data from randomized clinical trial

Background: The rate of Helicobacter pylori (H.pylori) eradication in dyspeptic patients using bismuth- based triple therapy is low due to bacterial that are resistant to antibiotics. The results of recent studies regarding levofloxacin have been encouraging, but the high cost of treatment prevents its routine administration. We, therefore, performed the present double-blind clinical trial to c...

متن کامل

Drug resistance pattern and clonality in H. pylori strains.

BACKGROUND This aim of this work was to determine the in vitro activity of clarithromycin, amoxycillin, metronidazole and tetracycline against Helicobacter pylori and clonality among resistant and sensitive strains isolated from North India. METHODOLOGY A total of 68 H. pylori isolates from peptic ulcer disease and non ulcer dyspepsia patients were examined. These strains were subjected for d...

متن کامل

Novel real-time PCR assay for detection of Helicobacter pylori infection and simultaneous clarithromycin susceptibility testing of stool and biopsy specimens.

A biprobe real-time PCR protocol, followed by hybridization melting point analysis, to detect point mutations in the 23S rRNA gene of Helicobacter pylori associated with clarithromycin resistance was established and evaluated in a clinical study. Of 92 patients who underwent endoscopy, 45 were found to be H. pylori infected and invariably were also culture positive. Of the 45 isolates, 11 were ...

متن کامل

A study on Antimicrobial Resistance of Helicobacter Pylori Isolates Recovered from Dyspeptic Patients by Epsilometer Test

The main purpose of the study is to determine resistance pattern of bacterial isolates to selected antibiotics among 88 dyspeptic patients in Iran. Frequency of infection among these patients have been evaluated among dyspeptic patients old (45 boys and 43 girls, aged 5-18 years) from 2016 to 2017.Eighty-eight patients with gastroduodenal disorders were included in the study. Urease test modifi...

متن کامل

Comparison between the effectiveness of Furazolidone and Clarithromycin on eradication of helicobacter pylori among patients with peptic ulcer

Introduction: Helicobacter pylori infections occur in about 50% of the world population and have a main role in the creation of peptic ulcer and its related cancer. We sought to evaluate the effectiveness of two treatment regimens on the eradication of helicobacter pylori and its complications among peptic ulcer patients. Materials and methods: By a clinical trial, patients with peptic ulcer ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 8  شماره 

صفحات  -

تاریخ انتشار 2004